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Senior Medical Director, Clinical Development (Rheumatology) | Remote

Spyre Therapeutics US- Remote 07/15/2026
Clinical Development Rheumatology Regulatory Strategy

About the Role

Spyre Therapeutics is seeking a Senior Medical Director to help shape and execute clinical development strategy for innovative therapies in rheumatology. This role is a key medical contributor within global clinical development programs, partnering closely with cross-functional teams to support study design, planning, protocol execution, and regulatory activities.

Responsibilities

  • Contribute to clinical development strategy for rheumatology indications and pipeline assets.
  • Support the design and implementation of study protocols, including scientific and medical input.
  • Partner with cross-functional teams to advance planning, execution, and oversight of clinical studies.
  • Provide clinical expertise to support regulatory interactions and related documentation.
  • Collaborate with internal stakeholders to ensure studies are aligned with program goals and patient needs.

Requirements

  • Experience in clinical development and medical leadership within the biopharmaceutical industry.
  • Strong knowledge of rheumatology and clinical trial execution.
  • Proven ability to partner cross-functionally across clinical, regulatory, and other teams.
  • Experience contributing to regulatory activities and protocol-related materials.

Benefits

  • Opportunity to help advance next-generation immunology therapies with meaningful patient impact.
  • Collaborate with a cross-functional, global clinical development team.
  • Remote work flexibility.
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Posted on July 15, 2026
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