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Senior Human Resources Manager (People Operations) | Onsite

People Operations Payroll Administration Onboarding & Offboarding

About the Role

Breeze Bio is seeking a full-time Senior Manager of People Operations to build and run the HR function end-to-end. This execution-first role reports directly to the Chief Operating Officer and is designed for someone who enjoys hands-on ownership of day-to-day people operations.

Responsibilities

  • Own payroll processing and ensure timely, accurate pay cycles
  • Manage onboarding and offboarding end-to-end, including required documentation
  • Screen candidates and support hiring workflows with a consistent, fair process
  • Be the primary point of contact for employee questions and issue resolution
  • Maintain and update compliance documentation to meet applicable requirements

Requirements

  • Proven experience in HR/People Operations with hands-on responsibility for core HR processes
  • Strong understanding of payroll workflows and employee lifecycle administration
  • Experience supporting recruiting activities, including candidate screening
  • Comfort operating in a fast-moving, early-stage environment
  • Strong attention to detail for compliance documentation and recordkeeping

Benefits

  • Opportunity to help shape HR operations at an early-stage, high-growth biotech company
  • Direct reporting line to the Chief Operating Officer
  • Collaborative, interdisciplinary culture focused on advancing genetic medicine
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Posted on July 13, 2026
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